Utility of Cardiopulmonary Exercise Testing in Assessing Beta‐Blocker Efficacy in LQTS: Moving Away From One‐Size‐Fits‐All
Adequate chronotropic suppression was achieved with "submaximal" beta blocker dose in 40%. Despite similar baseline risk profiles, LTEs were not significantly different in patients with submaximal versus maximal therapy. CPET may be a useful modality to devise an individualized treatment plan, especially in those who cannot tolerate the recommended guideline directed dose.
Authors
- Iqbal El Assaad (ORCID: https://orcid.org/0009-0005-5586-1945)
- Peter F. Aziz (ORCID: https://orcid.org/0000-0001-5971-5471)
- Alison K. Heilbronner (ORCID: https://orcid.org/0000-0001-8028-0062)
- Kenneth G. Zahka (ORCID: https://orcid.org/0000-0002-4556-8439)
- Benjamin H. Hammond (ORCID: https://orcid.org/0000-0002-9899-145X)
- Akash R. Patel (ORCID: https://orcid.org/0000-0002-8587-4780)
Institutions
- Cleveland Clinic (US)
- Primary Children's Hospital (US)
- Cleveland Clinic Lerner College of Medicine (US)
Publication Details
- Journal
- Journal of Cardiovascular Electrophysiology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1111/jce.70001
- Citations
- 1
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 1.39