Deficiency of Cartilage‐Specific Y‐Box Binding Protein 1 Represses <scp>NF</scp> ‐ <scp>κB</scp> Signaling and Alleviates Osteoarthritis Progression
YBX1 contributes to OA progression by inhibiting NKRF, activating NF-κB signaling; therefore, targeting YBX1 is a potential therapeutic strategy for the treatment of OA.
Authors
- Weihua Guo (ORCID: https://orcid.org/0000-0002-9580-513X)
- Jinwei Xie (ORCID: https://orcid.org/0000-0002-0623-6036)
- Zhenhan Deng (ORCID: https://orcid.org/0000-0003-0522-8269)
- Xinyu Li (ORCID: https://orcid.org/0000-0002-5908-6676)
- Zhao Zhang (ORCID: https://orcid.org/0000-0002-1389-7262)
- Zeyu Huang (ORCID: https://orcid.org/0000-0002-0456-8379)
Institutions
- City Of Hope National Medical Center (US)
- Union Hospital (HK)
- Sichuan University (CN)
- Wenzhou Medical University (CN)
- West China Medical Center of Sichuan University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- West China Hospital of Sichuan University (CN)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1002/art.43311
- Citations
- 2
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.34