Targeted photothermal therapy of hepatocellular carcinoma using gold nanoparticles functionalized with anti-cadherin and folic acid in a validated murine model
The GNPs-PEI-FA-Cad-1 system demonstrated promising results for targeted photothermal therapy in HCC, with selective tumor ablation and limited hepatotoxicity. The validated murine model provides a robust platform for preclinical assessment of similar nanotherapies.
Authors
- Lucian Mocan
- Maria Pia Cosma (ORCID: https://orcid.org/0000-0003-4207-5097)
- Romelia Pop (ORCID: https://orcid.org/0000-0003-0254-1823)
- Ofelia Moșteanu
- Teodora Mocan (ORCID: https://orcid.org/0000-0001-9925-0998)
- Flaviu Tăbăran (ORCID: https://orcid.org/0000-0001-5744-0451)
- Teodora Pop
Institutions
- Iuliu Hațieganu University of Medicine and Pharmacy (RO)
- University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca (RO)
Publication Details
- Journal
- Medicine and Pharmacy Reports
- Published
- 2025-07-14
- DOI
- https://doi.org/10.15386/mpr-2905
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00