A comprehensive dataset of therapeutic peptides on multi-function property and structure information
This paper presents a comprehensive dataset comprising 58,583 experimentally validated therapeutic peptides with annotated structure information. These peptides are grouped into 47 categories based on their function or therapeutic property like antimicrobial or glucose-regulatory, of which 21,130 are multi-function peptides and 54,722 possess structural annotation information. We believe this dataset can be useful for the relevant research of therapeutic peptides, especially for computational tool developments in therapeutic peptide discovery and further exploration of the 'sequence-structure-function' relationship for therapeutic peptides.
Authors
- Long Zhao
- Xuehai Fei (ORCID: https://orcid.org/0000-0002-1730-759X)
- Yong‐Biao Zhang (ORCID: https://orcid.org/0000-0002-2764-2148)
- Baichuan Xiao (ORCID: https://orcid.org/0000-0001-7608-8043)
- Yixiang Zhou (ORCID: https://orcid.org/0009-0004-0894-2040)
- Haodong Huang (ORCID: https://orcid.org/0000-0002-6109-8860)
Institutions
- Beijing Institute of Petrochemical Technology (CN)
- Ministry of Education of the People's Republic of China (CN)
- Wuhan University (CN)
- Beihang University (CN)
- Ministry of Industry and Information Technology (CN)
Publication Details
- Journal
- Scientific Data
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1038/s41597-025-05528-1
- Citations
- 4
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 4.73
Funders
- National Natural Science Foundation of China