Familial Aggregation in Psoriatic Arthritis: Phenotypic Differences in Patients With and Without a Family History of Psoriatic Disease

In this cohort, patients with PsA with a family history of psoriatic disease were diagnosed with psoriasis and PsA earlier and were more likely to have entheseal involvement compared to those without a family history. Further research incorporating molecular and immune features is needed to investigate genetic, environmental, and epigenetic factors that impact PsA phenotype and severity, as well as the transition from psoriasis to PsA.

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Publication Details

Journal
Arthritis & Rheumatology
Published
2025-07-14
DOI
https://doi.org/10.1002/art.43325
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Familial Aggregation in Psoriatic Arthritis: Phenotypic Differences in Patients With and Without a Family History of Psoriatic Disease

Rebecca H. Haberman, Weixi Chen, K. K. Chen, José U. Scher et al.
Arthritis & Rheumatology
Spondyloarthritis Studies and Treatments
article

Familial Aggregation in Psoriatic Arthritis: Phenotypic Differences in Patients With and Without a Family History of Psoriatic Disease

Rebecca H. Haberman, Weixi Chen, K. K. Chen, José U. Scher, Catherine Howe, Jiyuan Hu, Andrea L. Neimann, Soumya M. Reddy, Stephanie Eichman, Adamary Felipe, Eileen Lydon, Margaret Coyle
article en

Abstract

In this cohort, patients with PsA with a family history of psoriatic disease were diagnosed with psoriasis and PsA earlier and were more likely to have entheseal involvement compared to those without a family history. Further research incorporating molecular and immune features is needed to investigate genetic, environmental, and epigenetic factors that impact PsA phenotype and severity, as well as the transition from psoriasis to PsA.

Arthritis & RheumatologyVol. 78(1)
New York University (US)
Openalex Percentile: Top 72%
Spondyloarthritis Studies and Treatments
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Familial Aggregation in Psoriatic Arthritis: Phenotypic Differences in Patients With and Without a Family History of Psoriatic Disease — Rebecca H. Haberman, Weixi Chen, et al. · Arthritis & Rheumatology (2025) | TGRS Research Map | TGRS