THE EFFECT OF DIET ON THE BIOCHEMICAL, ACID-BASE AND GAS HOMEOSTASIS OF BLOOD

The aim of the present study was to establish the mechanism of diet (nutrition regime) effect on biochemical, acid-base and gas homeostasis of blood under experimental conditions. Diet, being an important component of the exposome - a set of factors of external and internal environment, as well as lifestyle – has a prolonged effect on the human body throughout life. Depending on its qualitative and quantitative composition, the diet can act as a therapeutic and prophylactic tool, contributing to the maintenance of homeostasis, and as a risk factor for the development of severe chronic pathologies. Among them are metabolic disorders (obesity, dysenergy of metabolic processes, imbalance of water-electrolyte and acid-base balance), diseases of the endocrine system (insulin resistance, type 2 diabetes mellitus), cardiovascular system (coronary heart disease, arterial hypertension), nervous system (dyscirculatory encephalopathy, acute cerebral circulation disorder), gastrointestinal tract (chronic gastritis, peptic ulcer disease, non-alcoholic fatty liver disease), and various forms of tissue dystrophies.