The efficacy and pharmacological mechanism of Guilingji to prevent Alzheimer’s disease
GLJ effectively delays AD progression by modulating critical pathological pathways such as neuronal survival, neuroinflammation, and Aβ clearance through a synergistic multi-target approach, offering a promising avenue for AD prevention.
Authors
- Bo Yang (ORCID: https://orcid.org/0000-0002-4130-6212)
- Yanlin Liang
- Yaling Lei (ORCID: https://orcid.org/0000-0003-3728-7335)
- Fengrui Hu (ORCID: https://orcid.org/0000-0002-8268-7373)
- Shan Wang (ORCID: https://orcid.org/0000-0002-9573-7579)
- Bei Zhang (ORCID: https://orcid.org/0000-0002-6704-1689)
- Xingchun Gou
- Rui Han
- Jing Luan
Institutions
- China National Pharmaceutical Group Corporation (China) (CN)
- Xi'an Medical University (CN)
- Shaanxi Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s13195-025-01790-y
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Education Department of Shaanxi Province
- Natural Science Basic Research Program of Shaanxi Province