A rare tumor with unique features: polymorphous low-grade neuroepithelial tumor of the young with third ventricular location and TP53 mutation. Illustrative case

The authors contribute a new case of PLNTY to the literature, highlighting the uncommon features of this case, including third ventricular localization and the presence of a TP53 mutation. They include a surgical case video for comprehensive visualization. These tumors typically exhibit indolent behavior and can be managed with resection alone. Comprehensive radiological, histological, and molecular evaluation is necessary to distinguish these tumors from other low-grade neoplasms. https://thejns.org/doi/10.3171/CASE25346.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-07-14
DOI
https://doi.org/10.3171/case25346
Primary Topic
Glioma Diagnosis and Treatment
Type
article
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article

A rare tumor with unique features: polymorphous low-grade neuroepithelial tumor of the young with third ventricular location and TP53 mutation. Illustrative case

Jeffrey Helgager, Ufuk Erginoğlu, Mustafa K. Başkaya, Miner N. Ross et al.
1 links
Journal of Neurosurgery Case Lessons
Glioma Diagnosis and Treatment
article

A rare tumor with unique features: polymorphous low-grade neuroepithelial tumor of the young with third ventricular location and TP53 mutation. Illustrative case

Jeffrey Helgager, Ufuk Erginoğlu, Mustafa K. Başkaya, Miner N. Ross, Cagdas Ataoglu, Zeynep Arzum Uyaniker
article en

Abstract

The authors contribute a new case of PLNTY to the literature, highlighting the uncommon features of this case, including third ventricular localization and the presence of a TP53 mutation. They include a surgical case video for comprehensive visualization. These tumors typically exhibit indolent behavior and can be managed with resection alone. Comprehensive radiological, histological, and molecular evaluation is necessary to distinguish these tumors from other low-grade neoplasms. https://thejns.org/doi/10.3171/CASE25346.

Journal of Neurosurgery Case LessonsVol. 10(2)
University of Wisconsin–Madison (US), Wisconsin Division of Public Health (US)
Good health and well-being
Openalex Percentile: Top 76%
Glioma Diagnosis and Treatment
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