A rare tumor with unique features: polymorphous low-grade neuroepithelial tumor of the young with third ventricular location and TP53 mutation. Illustrative case
The authors contribute a new case of PLNTY to the literature, highlighting the uncommon features of this case, including third ventricular localization and the presence of a TP53 mutation. They include a surgical case video for comprehensive visualization. These tumors typically exhibit indolent behavior and can be managed with resection alone. Comprehensive radiological, histological, and molecular evaluation is necessary to distinguish these tumors from other low-grade neoplasms. https://thejns.org/doi/10.3171/CASE25346.
Authors
- Jeffrey Helgager
- Ufuk Erginoğlu (ORCID: https://orcid.org/0000-0002-5387-4698)
- Mustafa K. Başkaya (ORCID: https://orcid.org/0000-0002-2782-4793)
- Miner N. Ross (ORCID: https://orcid.org/0009-0002-5175-9503)
- Cagdas Ataoglu (ORCID: https://orcid.org/0009-0009-6566-6034)
- Zeynep Arzum Uyaniker (ORCID: https://orcid.org/0009-0001-3410-1454)
Institutions
- University of Wisconsin–Madison (US)
- Wisconsin Division of Public Health (US)
Publication Details
- Journal
- Journal of Neurosurgery Case Lessons
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3171/case25346
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00