Long non-coding RNA SNHG16 promotes tumor progression and cisplatin resistance in esophageal squamous cell carcinoma via miR-497-5p/HK2 axis
Our findings uncovered that SNHG16 promoted ESCC malignant progression and DDP resistance through the miR-497-5p/HK2 axis, laying the groundwork for deciphering the molecular mechanisms underlying chemotherapy resistance in ESCC and developing new treatment strategies.
Authors
- Xiaofeng Zhu (ORCID: https://orcid.org/0000-0003-0037-411X)
- Yayun Cui (ORCID: https://orcid.org/0000-0001-7009-3765)
- Ming‐Hua Xie (ORCID: https://orcid.org/0000-0002-7959-6163)
Institutions
- University of Science and Technology of China (CN)
- Anhui Provincial Hospital (CN)
Publication Details
- Journal
- Journal of Cardiothoracic Surgery
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s13019-025-03528-1
- Citations
- 4
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 3.75