Localized Morphea in a Pediatric Patient Successfully Treated With Topical Ruxolitinib

Pediatric morphea is a rare disorder characterized by fibrosis of the skin and underlying structures. First-line treatment of localized, uncomplicated disease is typically with high-potency topical steroids. Literature on the treatment of localized recalcitrant disease is sparse. We report a case of biopsy-confirmed morphea in a 17-year-old female that significantly improved with topical ruxolitinib 1.5% cream and intralesional triamcinolone after treatment with clobetasol ointment failed.

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Publication Details

Journal
Pediatric Dermatology
Published
2025-07-13
DOI
https://doi.org/10.1111/pde.16025
Citations
2
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
2.94
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article

Localized Morphea in a Pediatric Patient Successfully Treated With Topical Ruxolitinib

Grace Rabinowitz, Justine Fenner, Nicholas Gulati, Saakshi Khattri
2 citations
Pediatric Dermatology
Systemic Sclerosis and Related Diseases
2.94
article

Localized Morphea in a Pediatric Patient Successfully Treated With Topical Ruxolitinib

Grace Rabinowitz, Justine Fenner, Nicholas Gulati, Saakshi Khattri
article en
2 citations

Abstract

Pediatric morphea is a rare disorder characterized by fibrosis of the skin and underlying structures. First-line treatment of localized, uncomplicated disease is typically with high-potency topical steroids. Literature on the treatment of localized recalcitrant disease is sparse. We report a case of biopsy-confirmed morphea in a 17-year-old female that significantly improved with topical ruxolitinib 1.5% cream and intralesional triamcinolone after treatment with clobetasol ointment failed.

Pediatric DermatologyVol. 42(6)
Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 9%
Systemic Sclerosis and Related Diseases
2.94
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