Reduced plasma oxytocin levels in patients with open-angle glaucoma
Oxytocin concentrations in glaucoma patients were significantly lower than in normal subjects and associated with the severity and progression of visual field defects. Given the wide variety of the pharmacological actions of oxytocin, it may be involved in the pathogenesis of glaucoma. Our results suggest that plasma oxytocin measurements may open a new avenue for glaucoma care.
Authors
- Naoki Kiyota (ORCID: https://orcid.org/0000-0003-4613-7048)
- Yu Yokoyama (ORCID: https://orcid.org/0000-0001-5275-2923)
- Noriko Himori (ORCID: https://orcid.org/0000-0001-8307-0458)
- Kazuko Omodaka
- Chiaki Yamaguchi
- Kota Sato (ORCID: https://orcid.org/0000-0002-0176-5545)
- Naoki Takahashi (ORCID: https://orcid.org/0000-0001-7572-5004)
- Yurina Yamada
- Satoru Tsuda
- Yoko Takeda
- Toru Nakazawa
Institutions
- Tohoku University (JP)
Publication Details
- Journal
- Japanese Journal of Ophthalmology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1007/s10384-025-01248-6
- Primary Topic
- Neuroendocrine regulation and behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Science and Technology Corporation
- Co-creation place formation support program
- JST-Mirai Program