Exploring the therapeutic mechanism of itraconazole combined with ritonavir on Candida albicans infection through network pharmacology and molecular docking
Network pharmacological analysis showed a multi-target and multi-pathway molecular mechanism of itraconazole and ritonavir in the treatment of <i>C. albicans</i> infection, and provided a theoretical basis for subsequent studies.
Authors
- Yan Ma (ORCID: https://orcid.org/0000-0003-4419-6001)
- Wenli Feng (ORCID: https://orcid.org/0000-0001-5510-7401)
- Yi Feng (ORCID: https://orcid.org/0000-0003-0001-6857)
- Jing Yang (ORCID: https://orcid.org/0000-0003-3801-3985)
Institutions
- Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fphar.2025.1578749
- Citations
- 1
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China