The role of probiotic supplementation in reducing Helicobacter pylori recurrence after classic quadruple therapy

Probiotic supplementation is associated with a reduced risk of <i>H. pylori</i> recurrence after classic quadruple therapy. In addition to improving gastrointestinal tolerance and adherence, probiotics may contribute to maintaining gut microbial balance and enhancing eradication durability. These findings support the integration of probiotics as an adjunct to standard therapy. Further randomized controlled trials are needed to confirm efficacy and identify optimal probiotic formulations and duration.