Effects of RAS and SGLT2 inhibitors alone or in combination on end-stage kidney disease and/or all-cause death in patients with both diabetes and hypertension: a nationwide cohort study
Combination therapy may provide the greatest renal and survival benefit for diabetic patients with hypertension. SGLT2 inhibitors alone significantly reduced mortality, while RAS inhibitors alone had a modest impact.
Authors
- Sangmo Hong
- Cheol‐Young Park (ORCID: https://orcid.org/0000-0002-9415-9965)
- Kyungdo Han (ORCID: https://orcid.org/0000-0002-6096-1263)
- Kyung‐Soo Kim (ORCID: https://orcid.org/0000-0002-7738-2284)
Institutions
- Soongsil University (KR)
- Hanyang University Guri Hospital (KR)
- CHA University Bundang Medical Center (KR)
- CHA University (KR)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1186/s12933-025-02846-x
- Citations
- 5
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.47
Funders
- National Health Insurance Service