Antibacterial, antifungal, and antibiofilm activities of biogenic zinc nanoparticles against pathogenic microorganisms
These antibiofilm activities were attributed to disruptions in cellular stress metabolism, primarily driven by nitrosative stress through enhanced production of reactive nitrogen intermediates. ZnNPs synthesized through green methods offer significant advantages due to their biocompatibility and potential biomedical applications. These findings advance our understanding of ZnNPs in combating biofilm-associated infections, offering promising strategies to address pathogenic bacteria and fungi, which pose a critical threat to global health.
Authors
- Natalia Guiñazú (ORCID: https://orcid.org/0000-0002-1215-6796)
- Pamela Soledad Bustos (ORCID: https://orcid.org/0000-0003-1521-9585)
- María Gabriela Paraje (ORCID: https://orcid.org/0000-0001-8600-1159)
- Karina F. Crespo Andrada
- Manuela Maldonado Torales
- Iván Manrrique Hughes
- Eliana Daniela Lopez Venditti
Institutions
- Universidad Nacional de Córdoba (AR)
- Instituto Multidisciplinario de Biología Vegetal (AR)
- Universidad Nacional del Comahue (AR)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fcimb.2025.1545119
- Citations
- 9
- Primary Topic
- Nanoparticles: synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 4.66
Funders
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Secretaria de Ciencia y Tecnología - Universidad Nacional de Córdoba
- Fondo para la Investigación Científica y Tecnológica