Transcriptome-guided engineering of a native niacin transporter in Lactiplantibacillus plantarum unveils metabolic rewiring for NMN biosynthesis
This combined transporter engineering and transcriptome-guided strategy establishes a food-grade <i>L. plantarum</i> platform for efficient NMN production in functional fermented foods.
Authors
- Lianzhong Ai (ORCID: https://orcid.org/0000-0002-6681-9102)
- Jiayang Qin (ORCID: https://orcid.org/0000-0002-1449-9215)
- Linghui Kong (ORCID: https://orcid.org/0000-0001-7330-3967)
- Xinyu Li (ORCID: https://orcid.org/0000-0002-5908-6676)
- Qing‐Yu He (ORCID: https://orcid.org/0000-0003-0503-9492)
- Qingshou Yao (ORCID: https://orcid.org/0009-0004-8808-2211)
Institutions
- Binzhou Medical University (CN)
- Shandong University of Aeronautics (CN)
- Shanghai Jiao Tong University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fmicb.2025.1637666
- Citations
- 2
- Primary Topic
- Probiotics and Fermented Foods
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province