Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Overall, these results highlight the synergistic impact of hyperglycemia and HgCl<sub>2</sub> exposure in exacerbating neuroinflammation and cognitive decline, suggesting a critical interaction between metabolic and environmental neurotoxic factors.

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Publication Details

Journal
Frontiers in Toxicology
Published
2025-07-14
DOI
https://doi.org/10.3389/ftox.2025.1610720
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Youssef Aboussaleh, Meriam El Aboubi, Samir Bikri, Fatima-Zahra Yassif et al.
Frontiers in Toxicology
Tryptophan and brain disorders
article

Subchronic effects of HgCl2 on cognitive function and central inflammation in type 2 diabetic rats: involvement of BDNF and acetylcholinesterase

Youssef Aboussaleh, Meriam El Aboubi, Samir Bikri, Fatima-Zahra Yassif, Douae Benloughmari
article en

Abstract

Overall, these results highlight the synergistic impact of hyperglycemia and HgCl<sub>2</sub> exposure in exacerbating neuroinflammation and cognitive decline, suggesting a critical interaction between metabolic and environmental neurotoxic factors.

Frontiers in ToxicologyVol. 7
Université Ibn-Tofail (MA)
Good health and well-being
Openalex Percentile: Top 84%
Tryptophan and brain disorders
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