Inhibition of BET proteins modulates amyloid-beta accumulation and cognitive performance in middle-aged mice prenatally exposed to maternal immune activation
Our findings suggest that inhibition of BET proteins may effectively attenuate neuropathological alterations in the aged brain.
Authors
- Ewelina Pałasz (ORCID: https://orcid.org/0000-0001-8938-3762)
- Magdalena Gąssowska-Dobrowolska (ORCID: https://orcid.org/0000-0001-9777-1378)
- Grzegorz A. Czapski (ORCID: https://orcid.org/0000-0002-7541-1571)
- Marta Matuszewska (ORCID: https://orcid.org/0000-0002-5996-7799)
- Marcin Strawski (ORCID: https://orcid.org/0000-0002-8253-0878)
- Anna Wilkaniec (ORCID: https://orcid.org/0000-0002-1121-5168)
- Gabriela Olech-Kochańczyk
- Magdalena Cieślik (ORCID: https://orcid.org/0000-0002-7604-4371)
- Elżbieta Gawinek
Institutions
- Mossakowski Medical Research Institute, Polish Academy of Sciences (PL)
- University of Warsaw (PL)
Publication Details
- Journal
- Frontiers in Molecular Neuroscience
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fnmol.2025.1619583
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- Narodowe Centrum Nauki