Long‐acting injectable paliperidone palmitate for severe anorexia nervosa and comorbid autism spectrum disorder: A case report

This case highlights the potential role of LAI paliperidone palmitate in managing treatment-refractory AN with comorbid ASD and intellectual disability, particularly in patients with poor adherence and prominent obsessive traits. Although antipsychotics are not standard for AN, LAI formulations may offer pragmatic, sustainable benefits in selected cases. Further studies are warranted to assess long-term safety and efficacy in this population.

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Publication Details

Journal
Psychiatry and Clinical Neurosciences Reports
Published
2025-07-13
DOI
https://doi.org/10.1002/pcn5.70161
Primary Topic
Autism Spectrum Disorder Research
Type
article
Field-Weighted Citation Impact
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article

Long‐acting injectable paliperidone palmitate for severe anorexia nervosa and comorbid autism spectrum disorder: A case report

Yuhei Mori, Itaru Miura, Y Suzuki
Psychiatry and Clinical Neurosciences Reports
Autism Spectrum Disorder Research
article

Long‐acting injectable paliperidone palmitate for severe anorexia nervosa and comorbid autism spectrum disorder: A case report

Yuhei Mori, Itaru Miura, Y Suzuki
article en

Abstract

This case highlights the potential role of LAI paliperidone palmitate in managing treatment-refractory AN with comorbid ASD and intellectual disability, particularly in patients with poor adherence and prominent obsessive traits. Although antipsychotics are not standard for AN, LAI formulations may offer pragmatic, sustainable benefits in selected cases. Further studies are warranted to assess long-term safety and efficacy in this population.

Psychiatry and Clinical Neurosciences ReportsVol. 4(3)
Fukushima Medical University (JP)
Zero hunger
Openalex Percentile: Top 84%
Autism Spectrum Disorder Research
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