Titanium Dioxide Nanoparticle Synthesized Via Sol-Gel Method for Water Purification and Evaluation of Biological Activities

Titanium dioxide is an extremely active in a variety of reactions, nontoxic, and reasonably priced and it also used extensively in water purification processes such as photocatalysis, catalysis, and dye degradation. Titanium dioxide nanoparticles (TiO2 NPs) potent oxidizing ability through the production of free radicals promotes the inactivation of bacteria by reducing their development. TiO2 NPs, using the sol-gel method, titanium precursors are combined with isopropanol, deionized water, and acids to create titanium dioxide nanoparticles. The present study focused on characterization and evaluation of synthetic TiO2 NPs for its anti-inflammatory, antioxidant and antimicrobial ability. Anti-inflammatory activity tested using bovine serum albumin/anti-denaturation assay, In-vitro antioxidant assay by (DPPH) and antibacterial activity by Agar well diffusion method was also performed. At a concentration of 100 µg/ml, the results showed that chemically produced TiO2 NPs have the ability to scavenge the free radical DPPH, neutralizing 72% of the radicals. It was shown that a sample of 100 µl of TiO2 NPs had strong anti-inflammatory properties and inhibited 69% of protein denaturation. TiO2 NPs were tested against pathogenic bacterial strains at varying concentrations (50, 75, and 100 mg/ml), they demonstrated significant antibacterial activity by inhibiting both Gram positive and Gram-negative bacteria. In the present study the prepared TiO2 NPs showed potent water purification property in the artificial polluted water.