Elevated plasma levels of WAP four-disulfide core domain 2 as a potential prognostic biomarker for various cancers
Plasma WFDC2 levels demonstrated potential diagnostic performance across multiple cancers and were significantly associated with poor prognosis in gastric and esophageal cancers.
Authors
- Kiyoshi Yoshimura (ORCID: https://orcid.org/0000-0003-4816-1826)
- Hirotsugu Ariizumi (ORCID: https://orcid.org/0000-0003-1663-8730)
- Ryotaro Ohkuma (ORCID: https://orcid.org/0000-0003-4121-2491)
- Atsushi Horiike (ORCID: https://orcid.org/0000-0002-1632-3125)
- Katsuaki Ieguchi (ORCID: https://orcid.org/0000-0002-8509-846X)
- Takashi Shimizu (ORCID: https://orcid.org/0000-0003-1294-0799)
- Shinichi Kobayashi (ORCID: https://orcid.org/0000-0002-1321-3908)
- Tomoyuki Ishiguro
- Masahiro Shimokawa (ORCID: https://orcid.org/0000-0002-8645-4112)
- Satoshi Wada (ORCID: https://orcid.org/0000-0001-6528-5914)
- Nana Iriguchi
- Yuji Kiuchi (ORCID: https://orcid.org/0000-0001-7198-3735)
- Yuya Hirasawa
- Makoto Watanabe (ORCID: https://orcid.org/0000-0002-6147-7713)
- Mayumi Tsuji (ORCID: https://orcid.org/0000-0002-9579-4418)
- Go Ikeda (ORCID: https://orcid.org/0000-0002-4373-9193)
- Emiko Mura
- Nobuyuki Onishi
- Risako Suzuki
- Takuya Tsunoda
Institutions
- SHOWA Medical University (JP)
- Therapeutics Clinical Research (US)
- SHOWA Medical University Hospital (JP)
- Showa Pharmaceutical University (JP)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fonc.2025.1614102
- Citations
- 1
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.70