Dopamine D2 receptor gene Taq 1A polymorphism: genetic architecture in Indian population and comparison to global populations

The present study observed a T allele frequency of 43%, comparable with the Asian population. In the comparison study, the T allele frequency in Global, Asian, Indian, and present studies was calculated as 26%, 35%, 33%, and 43%, respectively. This geographical gradient is clinically important in determination of the risk assessment which might be included in prevention strategies for psychiatric disorders.