Exploration of differential expression and biological significance of amino acid metabolism genes in osteoarthritis
This investigation presents a detailed evaluation of AAMRGs in OA, highlighting their roles in disease pathogenesis and offering new insights for therapeutic research. Key genes <i>SLC2A4, MTHDF2</i>, and <i>WNT5B</i> might function as markers for early identification and personalized OA treatment.
Authors
- Zhenghuan Zhu
- Kejie Wang (ORCID: https://orcid.org/0000-0001-5086-2299)
- Lingmin Hu
- Wanchao Zhang (ORCID: https://orcid.org/0000-0002-3735-7834)
- Jinliang Meng
- Hu Junfeng
- Lin Feng (ORCID: https://orcid.org/0000-0003-0951-713X)
- Wenge Ding
- Chuang Zhao
Institutions
- Soochow University (CN)
- The First People's Hospital of Changzhou (CN)
- Xinqiao Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Fuzhou Maternity and Child Health Care Hospital (CN)
- First Affiliated Hospital of Soochow University (CN)
- Changzhou Third People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-07-14
- DOI
- https://doi.org/10.3389/fimmu.2025.1588072
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00