Linear <scp>IgA</scp> Vasculitis: Cutaneous Small‐Vessel Leukocytoclastic Vasculitis, in Association With Linear <scp>IgA</scp> Disease‐Type Immunoreactant Deposition Along Epidermal Basement Membrane Zone

We present a 69-year-old male with overlapping clinical-histopathological-immunological features of cutaneous leukocytoclastic vasculitis (LCV) and linear IgA disease (LAD). The patient's disease was considered idiopathic, with a possible underlying infectious trigger/etiology. The term "linear IgA vasculitis" is proposed to describe those patients with rarely reported combined LCV-LAD findings, and includes idiopathic, drug-induced, and paraneoplastic causes.

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Journal
Journal of Cutaneous Pathology
Published
2025-07-13
DOI
https://doi.org/10.1111/cup.14843
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
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article

Linear IgA Vasculitis: Cutaneous Small‐Vessel Leukocytoclastic Vasculitis, in Association With Linear IgA Disease‐Type Immunoreactant Deposition Along Epidermal Basement Membrane Zone

Albert E Zhou, Timothy Klufas, Joseph Beauchemin, Michael J. Murphy et al.
Journal of Cutaneous Pathology
Autoimmune Bullous Skin Diseases
article

Linear IgA Vasculitis: Cutaneous Small‐Vessel Leukocytoclastic Vasculitis, in Association With Linear IgA Disease‐Type Immunoreactant Deposition Along Epidermal Basement Membrane Zone

Albert E Zhou, Timothy Klufas, Joseph Beauchemin, Michael J. Murphy, Shannon Hanggodo
article en

Abstract

We present a 69-year-old male with overlapping clinical-histopathological-immunological features of cutaneous leukocytoclastic vasculitis (LCV) and linear IgA disease (LAD). The patient's disease was considered idiopathic, with a possible underlying infectious trigger/etiology. The term "linear IgA vasculitis" is proposed to describe those patients with rarely reported combined LCV-LAD findings, and includes idiopathic, drug-induced, and paraneoplastic causes.

Journal of Cutaneous PathologyVol. 52(10)
New York Medical College (US), Quinnipiac University (US), UConn Health (US)
Good health and well-being
Openalex Percentile: Top 75%
Autoimmune Bullous Skin Diseases
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Linear <scp>IgA</scp> Vasculitis: Cutaneous Small‐Vessel Leukocytoclastic Vasculitis, in Association With Linear <scp>IgA</scp> Disease‐Type Immunoreactant Deposition Along Epidermal Basement Membrane Zone — Albert E Zhou, Timothy Klufas, et al. · Journal of Cutaneous Pathology (2025) | TGRS Research Map | TGRS