Skin manifestations in systemic scleroderma

Systemic scleroderma is a chronic disease whose etiology is not fully understood, characterized by diffuse changes in the skin with the development of fibrosis, as well as damage to internal organs (in particular, the esophagus, lower gastrointestinal tract, heart, liver, and kidneys). The disease can occur in a generalized and focal form, and it is also possible to develop a variant of scleroderma without skin damage. The typical clinical picture of the disease is characterized by damage to the skin, the occurrence of multiple joint lesions, the development of dysphagia, heartburn, general swelling, and the formation of finger contractures. In women, the disease occurs 4 times more often than in men, and is very rare in children. The onset of the disease is usually observed between the ages of 30 and 50. The diagnosis is established based on the clinical picture, taking into account laboratory test data. There is no specific treatment, and therapeutic measures are usually aimed at combating complication