Acrokeratoelastoidosis of Costa: Clinical

In this instance, we present a case involving a 42-year-old woman with no significant medical history who came to our dermatological clinic due to chronic, asymptomatic red-violet papules located on the sides of both feet (Fig. 1). These lesions had developed gradually over the past five years. The patient also noted that both of her sisters had similar lesions since childhood. Dermatoscopic examination revealed groups of white to violet papules, some exhibiting umbilication, interspersed with areas lacking distinct structures. A skin biopsy indicated the presence of hyalinized collagen and fragments of elastic fibers, with no signs of granulomatous areas, inflammatory infiltrate, or leukocytoclastic vasculitis. Consequently, we established a diagnosis of acrokeratoelastoidosis of Costa. Treatment involving a 10% salicylic acid cream was attempted for one month but yielded no improvement. Strong corticosteroids were somewhat effective in enhancing the lesions’purplish appearance and slightly reducing their size. However, the patient subsequently discontinued follow-up.

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Publication Details

Published
2025-07-13
DOI
https://doi.org/10.46889/jdr.2025.6212
Primary Topic
Genetic and rare skin diseases.
Type
article
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article

Acrokeratoelastoidosis of Costa: Clinical

Meryem Khalidi
Genetic and rare skin diseases.
article

Acrokeratoelastoidosis of Costa: Clinical

Meryem Khalidi
article en

Abstract

In this instance, we present a case involving a 42-year-old woman with no significant medical history who came to our dermatological clinic due to chronic, asymptomatic red-violet papules located on the sides of both feet (Fig. 1). These lesions had developed gradually over the past five years. The patient also noted that both of her sisters had similar lesions since childhood. Dermatoscopic examination revealed groups of white to violet papules, some exhibiting umbilication, interspersed with areas lacking distinct structures. A skin biopsy indicated the presence of hyalinized collagen and fragments of elastic fibers, with no signs of granulomatous areas, inflammatory infiltrate, or leukocytoclastic vasculitis. Consequently, we established a diagnosis of acrokeratoelastoidosis of Costa. Treatment involving a 10% salicylic acid cream was attempted for one month but yielded no improvement. Strong corticosteroids were somewhat effective in enhancing the lesions’purplish appearance and slightly reducing their size. However, the patient subsequently discontinued follow-up.

Openalex Percentile: Top 80%
Genetic and rare skin diseases.
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