Sesamin protects against Acetaminophen-induced nephrotoxicity by suppressing HMOX1-mediated apoptosis and ferroptosis
Ses alleviates APAP-induced renal injury by mediating the inhibition of ferroptosis and apoptosis via HMOX1. This study provides a new strategy for the prevention and treatment of drug-induced renal injury.
Authors
- Jingyi Ren (ORCID: https://orcid.org/0000-0002-9424-4713)
- Huanting Pei
- Siqi Zhu (ORCID: https://orcid.org/0000-0001-6307-1189)
- Bowen Yin (ORCID: https://orcid.org/0000-0001-7974-3445)
- Yuxia Ma (ORCID: https://orcid.org/0000-0002-3926-2644)
- Ziqian Zeng (ORCID: https://orcid.org/0000-0001-5300-6906)
- Zhenao Zhang
- Ruonan Zhang (ORCID: https://orcid.org/0000-0002-6987-3606)
- Xiaoya Sun (ORCID: https://orcid.org/0000-0003-3770-1997)
- Yadong Zhang
- Ziyi Wang (ORCID: https://orcid.org/0000-0002-9604-0335)
Institutions
- Hebei Medical University (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1080/13510002.2025.2529695
- Citations
- 3
- Primary Topic
- Sesame and Sesamin Research
- Type
- article
- Field-Weighted Citation Impact
- 5.25
Funders
- National Natural Science Foundation of China