Depth-dependent fluence compensation without a priori knowledge of tissue composition for quantitative ultrasound-guided photoacoustic imaging
Regardless of the varying geometries used for light delivery in photoacoustic imaging, it is feasible to perform ultrasound-guided photoacoustic imaging with simultaneous mechanical displacement of tissue to determine the effective optical attenuation coefficient of bulk tissue along the light path to the target.
Authors
- Xinyue Huang (ORCID: https://orcid.org/0000-0001-5202-3368)
- David Qin (ORCID: https://orcid.org/0000-0001-9963-4641)
- Timothy Sowers (ORCID: https://orcid.org/0000-0001-9293-0472)
- Stanislav Emelianov (ORCID: https://orcid.org/0000-0002-7098-133X)
- Donald VanderLaan
Institutions
- Georgia Institute of Technology (US)
- The Wallace H. Coulter Department of Biomedical Engineering (US)
- Bioengineering Center (RU)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1117/1.jbo.30.7.076005
- Primary Topic
- Photoacoustic and Ultrasonic Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Breast Cancer Research Foundation
- National Institutes of Health