Impact of baseline glucocorticoid use on the efficacy of immunotherapy combined with intracranial radiotherapy in NSCLC patients with brain metastases
Increased baseline GCs use is associated with reduced efficacy of the combination therapy in these patients and baseline high-dose GCs use (≥ 100 mg) notably impairs survival outcomes.
Authors
- Zaicheng Xu (ORCID: https://orcid.org/0000-0002-2870-1365)
- Zhenzhou Yang (ORCID: https://orcid.org/0000-0003-2496-1992)
- Hongjun Tang (ORCID: https://orcid.org/0000-0001-5491-3903)
- Shunping Huang (ORCID: https://orcid.org/0000-0002-7025-4917)
- Yuan Peng (ORCID: https://orcid.org/0000-0001-9563-9568)
- Yu‐Sheng Huang (ORCID: https://orcid.org/0000-0002-1119-7836)
- Hongtao Jian
- Jin Xiong
- Wenhao Shi (ORCID: https://orcid.org/0000-0003-3638-0626)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Community Health Center (US)
- Chongqing Cancer Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf158
- Citations
- 1
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- China Postdoctoral Science Foundation
- Chongqing Medical University