NUDT15 polymorphism-induced severe neutropenia in a young male with precursor T-cell acute lymphoblastic leukemia

The management of acute lymphoblastic leukemia (ALL) involves intensive chemotherapy which can lead to significant myelosuppression. Here we present a case of ALL who experienced severe neutropenia during maintenance therapy due to a NUDT15 polymorphism.

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Publication Details

Journal
Journal of Medical and Allied Sciences
Published
2025-01-01
DOI
https://doi.org/10.5455/jmas.214188
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

NUDT15 polymorphism-induced severe neutropenia in a young male with precursor T-cell acute lymphoblastic leukemia

Krishna Lakhani, Jignesh Patel, Rajendra G. Desai
Journal of Medical and Allied Sciences
RNA modifications and cancer
article

NUDT15 polymorphism-induced severe neutropenia in a young male with precursor T-cell acute lymphoblastic leukemia

Krishna Lakhani, Jignesh Patel, Rajendra G. Desai
article en

Abstract

The management of acute lymphoblastic leukemia (ALL) involves intensive chemotherapy which can lead to significant myelosuppression. Here we present a case of ALL who experienced severe neutropenia during maintenance therapy due to a NUDT15 polymorphism.

Journal of Medical and Allied SciencesVol. 15(1)
Openalex Percentile: Top 85%
RNA modifications and cancer
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NUDT15 polymorphism-induced severe neutropenia in a young male with precursor T-cell acute lymphoblastic leukemia — Krishna Lakhani, Jignesh Patel, et al. · Journal of Medical and Allied Sciences (2025) | TGRS Research Map | TGRS