Self‐supervised data‐driven approach defines pathological high‐frequency oscillations in epilepsy
Our data-driven approach using the generative artificial intelligence model yielded a novel, explainable definition of pathological HFOs, which has the potential to further enhance the clinical use of HFOs for EZ delineation.
Authors
- Aria Fallah (ORCID: https://orcid.org/0000-0002-9703-0964)
- Eishi Asano (ORCID: https://orcid.org/0000-0001-8391-4067)
- Yuanyi Ding (ORCID: https://orcid.org/0009-0006-5566-675X)
- Atsuro Daida (ORCID: https://orcid.org/0000-0003-1350-7700)
- Noriko Salamon (ORCID: https://orcid.org/0000-0002-3520-9467)
- Hiroki Nariai (ORCID: https://orcid.org/0000-0002-8318-2924)
- Shaun A. Hussain (ORCID: https://orcid.org/0000-0001-6947-8852)
- Lawrence Liu (ORCID: https://orcid.org/0009-0005-7579-5084)
- Joe X Qiao (ORCID: https://orcid.org/0000-0003-0089-7930)
- Myung‐Shin Sim (ORCID: https://orcid.org/0000-0001-9706-1499)
- Vwani Roychowdhury (ORCID: https://orcid.org/0000-0003-0832-6489)
- Chenda Duan (ORCID: https://orcid.org/0009-0003-8652-3960)
- Shingo Oana
- Naoto Kuroda (ORCID: https://orcid.org/0000-0003-1977-4893)
- Sotaro Kanai (ORCID: https://orcid.org/0000-0002-7320-2346)
- Raman Sankar (ORCID: https://orcid.org/0000-0002-5609-0362)
- Tonmoy Monsoor
- Jerome Engel (ORCID: https://orcid.org/0000-0001-6324-5716)
- Richard J. Staba (ORCID: https://orcid.org/0000-0003-2285-5627)
- Yipeng Zhang (ORCID: https://orcid.org/0000-0003-2869-4692)
Institutions
- Children’s Institute (US)
- University of California, Los Angeles (US)
- Wayne State University (US)
- Children's Hospital of Michigan (US)
- Olive View-UCLA Medical Center (US)
- Mattel Children's Hospital (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1111/epi.18545
- Citations
- 4
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.88
Funders
- National Institute of Neurological Disorders and Stroke
- National Center for Advancing Translational Sciences
- Children's Discovery and Innovation Institute, University of California, Los Angeles