Congenital Corneal Anesthesia Secondary to Brainstem Ischemia as a Rare Complication of Neonatal Hypoxic-Ischemic Encephalopathy

We report the case of a very rare instance of congenital corneal anesthesia secondary to brainstem lesions following neonatal hypoxic-ischemic encephalopathy. It's the case of a 7-month-old baby with a history of neonatal asphyxia who presented with spontaneous corneal ulcerations and corneal anesthesia associated with brainstem lesions and brain lesions visible on MRI, secondary to neonatal hypoxic-ischemic encephalopathy. The case of the baby was complicated by the superinfection of the ulceration. He was treated with fortified antibiotics, eyedrops, and frequent instillation of eye lubricants and ointments. The evolution was marked by the healing of the ulceration and the improvement of the corneal sensitivity; however, there were sequelae in the more affected eye by the formation of a corneal pannus.

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Publication Details

Journal
Cureus
Published
2025-07-12
DOI
https://doi.org/10.7759/cureus.87777
Citations
1
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
Field-Weighted Citation Impact
1.32
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Congenital Corneal Anesthesia Secondary to Brainstem Ischemia as a Rare Complication of Neonatal Hypoxic-Ischemic Encephalopathy

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article

Congenital Corneal Anesthesia Secondary to Brainstem Ischemia as a Rare Complication of Neonatal Hypoxic-Ischemic Encephalopathy

Mohammed Frarchi, Nabil Bouslous, Jalal Laakri, Khaoula Ajbar, Omar Moustaine
article en
1 citations

Abstract

We report the case of a very rare instance of congenital corneal anesthesia secondary to brainstem lesions following neonatal hypoxic-ischemic encephalopathy. It's the case of a 7-month-old baby with a history of neonatal asphyxia who presented with spontaneous corneal ulcerations and corneal anesthesia associated with brainstem lesions and brain lesions visible on MRI, secondary to neonatal hypoxic-ischemic encephalopathy. The case of the baby was complicated by the superinfection of the ulceration. He was treated with fortified antibiotics, eyedrops, and frequent instillation of eye lubricants and ointments. The evolution was marked by the healing of the ulceration and the improvement of the corneal sensitivity; however, there were sequelae in the more affected eye by the formation of a corneal pannus.

CureusVol. 17(7)
Régie Autonome Multi Services D'Agadir (MA)
Openalex Percentile: Top 19%
Anesthesia and Neurotoxicity Research
1.32
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