The evolving epidemiology of Carbapenemase-producing Enterobacterales in Canadian acute care facilities, 2010–2023
Surveillance data from a national network of Canadian acute care hospitals indicates that while the incidence of CPE in Canada remains low, it is accelerating at an exponential rate. Our findings suggest that nosocomial transmission is driving the recent increase in CPE incidence in Canada. Improved infection control measures and antimicrobial stewardship as well as access to newer antimicrobials are all urgently needed.
Authors
- Santina Lee
- Pamela Kibsey
- Yves Longtin (ORCID: https://orcid.org/0000-0002-4532-379X)
- Connie Patterson
- Allison McGeer (ORCID: https://orcid.org/0000-0001-5647-6137)
- Laura F. Mataseje (ORCID: https://orcid.org/0000-0002-8014-1107)
- Tamara Duncombe (ORCID: https://orcid.org/0000-0002-8182-5615)
- Jocelyn A. Srigley (ORCID: https://orcid.org/0000-0002-0030-7665)
- Jen Tomlinson
- Nisha Thampi (ORCID: https://orcid.org/0000-0003-0208-6277)
- Sonja Musto
- Kristine Cannon
- Susy Hota (ORCID: https://orcid.org/0000-0002-3911-7033)
- Kathryn N. Suh (ORCID: https://orcid.org/0000-0002-8073-0243)
- Jerome A. Leis (ORCID: https://orcid.org/0000-0003-2250-4894)
- Jessica Minion (ORCID: https://orcid.org/0000-0002-8863-5697)
- Kevin Katz
- Joëlle Cayen
- Erin McGill (ORCID: https://orcid.org/0000-0003-2856-3334)
- Kristen Versluys
- Joseph Vayalumkal
- Xena X. Li (ORCID: https://orcid.org/0000-0003-1510-6310)
- Ewa Rajda
- Stephanie Smith (ORCID: https://orcid.org/0000-0002-4910-0083)
- Jennifer Happe (ORCID: https://orcid.org/0009-0007-5407-6552)
- Ian Davis (ORCID: https://orcid.org/0000-0002-4048-6856)
- Jennifer Ellison (ORCID: https://orcid.org/0000-0001-6278-9519)
- Titus Wong
- Chelsey Ellis
- Robyn Mitchell (ORCID: https://orcid.org/0000-0002-6241-196X)
Institutions
- Interior Health (CA)
- Alberta Health Services (CA)
- Island Health (CA)
- Dalhousie University (CA)
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- University of Alberta (CA)
- Provincial Health Services Authority (CA)
- Public Health Agency of Canada (CA)
- Fraser Health (CA)
- Saskatchewan Health Authority (CA)
- Children's Hospital of Eastern Ontario (CA)
- Saskatchewan Health (CA)
- Moncton Hospital (CA)
- North York General Hospital (CA)
- Ottawa Hospital (CA)
- McGill University Health Centre (CA)
- Jewish General Hospital (CA)
- Alberta Children's Hospital (CA)
- Health Sciences Centre (CA)
- Children's & Women's Health Centre of British Columbia (CA)
- Sinai Health System (CA)
- BC Children's Hospital (CA)
- B.C. Women's Hospital & Health Centre (CA)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1186/s13756-025-01602-w
- Citations
- 5
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 2.96
Funders
- Public Health Agency of Canada
- Public Health Agency