Differentially expressed growth factors and cytokines drive phenotypic changes in transmissible cancers
These findings suggest complex interactions between cytokine signalling, phenotypic plasticity, growth and survival of DFTs. Signalling pathways implicated in the propagation of DFT are potential targets for therapeutic intervention and vaccine development for Tasmanian devil conservation.
Authors
- Amanda L. Patchett (ORCID: https://orcid.org/0000-0002-8424-4680)
- Anna Schönbichler (ORCID: https://orcid.org/0009-0001-5914-7782)
- Kathryn G. Maskell (ORCID: https://orcid.org/0000-0002-0935-1558)
- Andrew S. Flies (ORCID: https://orcid.org/0000-0002-4550-1859)
Institutions
- Commonwealth Scientific and Industrial Research Organisation (AU)
- University of Tasmania (AU)
- University of Veterinary Medicine Vienna (AT)
- Animal, Food and Health Sciences (AU)
Publication Details
- Journal
- Discovery Immunology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/discim/kyaf011
- Citations
- 2
- Primary Topic
- Veterinary Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- University of Tasmania
- Australian Research Council