[Clinical Characteristics, MAML2 Gene Rearrangement and Prognosis of Pulmonary Mucoepidermoid Carcinoma].
PMEC exhibits distinct clinicopathological features, with MAML2 rearrangement present in approximately half of cases. Lymph node metastasis, advanced stage, high Ki-67 proliferation index, and high-grade histology are key determinants of poor prognosis, with lymph node metastasis serving as an independent risk factor.
Authors
- Weishuo Liu (ORCID: https://orcid.org/0000-0002-3567-0755)
- Jianrong Bai
- Jiao Li (ORCID: https://orcid.org/0000-0003-1037-2732)
- Yan Meng (ORCID: https://orcid.org/0000-0002-0614-8968)
- Zhe Lei (ORCID: https://orcid.org/0000-0002-5220-7391)
- Zigui Zou
- Yushuang Zheng
- Lingchuan Guo (ORCID: https://orcid.org/0000-0002-1028-9296)
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-20
- DOI
- https://doi.org/10.3779/j.issn.1009-3419.2025.101.10
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article