Retrospective Multicenter Chart Review Study of Adjunctive Cannabidiol for Seizures Associated with Lennox–Gastaut Syndrome, Dravet Syndrome and Tuberous Sclerosis Complex
In patients with LGS, DS, or TSC-associated epilepsy, adjunctive CBD was associated with a reduction in seizure frequency across age groups. CBD demonstrated tolerability consistent with its known profile, and 67% of patients remained on treatment at 12 months.
Authors
- Kerstin Alexandra Klotz (ORCID: https://orcid.org/0000-0002-1601-5384)
- Felix von Podewils (ORCID: https://orcid.org/0000-0002-3134-8697)
- Ilka Immisch
- Susanne Knake (ORCID: https://orcid.org/0000-0002-6298-0513)
- Susanne Schubert‐Bast (ORCID: https://orcid.org/0000-0003-1545-7364)
- Felix Rosenow (ORCID: https://orcid.org/0000-0002-3989-7471)
- Adam Strzelczyk (ORCID: https://orcid.org/0000-0001-6288-9915)
- Gerhard Kurlemann
- Elisa Buhleier
- Luise Herold
Institutions
- Goethe University Frankfurt (DE)
- University of Freiburg (DE)
- Philipps University of Marburg (DE)
- Universitätsmedizin Greifswald (DE)
- University Hospital Bonn (DE)
- University Hospital Frankfurt (DE)
- Epilepsiezentrum Kleinwachau Gemeinnützige (DE)
- St. Bonifatius Hospital (DE)
Publication Details
- Journal
- Neurology and Therapy
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1007/s40120-025-00788-w
- Citations
- 2
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Jazz Pharmaceuticals