Guilty by association: direct interaction with the tetraspanin CD63 suggests a role for organic cation transporter 3 in histamine release from granulocytes
In conclusion, OCT3 is a transporter for histamine in granulocytes, which plays a crucial role in determining the intensity of allergic reactions and may be a target for interventions aimed at reducing their severity.
Authors
- Giuliano Ciarimboli (ORCID: https://orcid.org/0000-0002-4365-3656)
- S. A. Gotz (ORCID: https://orcid.org/0000-0002-7518-7055)
- Thomas Vogl (ORCID: https://orcid.org/0000-0001-9669-7479)
- Rouvier Al-Monajjed
- Ute Neugebauer
- Miriam Dibos (ORCID: https://orcid.org/0000-0001-7778-3283)
- Christian Albiker
- R. Verena Taudte (ORCID: https://orcid.org/0000-0003-4617-6063)
- Vivien Barz
- Moritz Pernecker
- Rita Schröter
- Lena Ludwig-Radtke
Institutions
- Philipps University of Marburg (DE)
- University of Münster (DE)
- University Hospital Münster (DE)
Publication Details
- Journal
- Journal of Biomedical Science
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1186/s12929-025-01158-2
- Citations
- 1
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- Deutsche Forschungsgemeinschaft