Effect of Intra-Ligamental Injection Before Removal of Spinal Needle After Spinal Anesthesia on Post Spinal Headache, no Injection Versus Normal Saline Versus Dexamethasone

Among the most frequent side effects of spinal anesthesia is post-dural puncture headache (PDPH), which occurs in 1-40% of scenarios. In forty percent of cases, invasive treatment options such as epidural blood patches may be necessary, and it might result in significant comorbidity. The dural healing is facilitated by fibroblastic growth; this growth is thought to be enhanced by the damage to the surrounding tissues and the presence of a blood clot. Needle trauma, normal saline and dexamethasone all can produce local irritation that might enhance fibroblastic proliferation. Aim of the study: Assessment of intra-ligamental injection of normal saline and dexamethasone on the incidence, duration and severity of post-spinal headache following spinal anesthesia. Patients and Methods: 75 patients were randomly selected and enrolled into this study. They were divided into three equal groups; control group (C) received nothing, group (D) received dexamethasone, and group (N) received normal saline. After performing spinal block with heavy bupivacaine, in groups D and N the needle was withdrawn for about 0.5 cm to make sure the tip of the needle is in the interspinous ligament then either 1 ml of normal saline or 1 ml of dexamethasone solution was injected before complete removal of the needle. The incidence, severity, onset, and duration of PDPH were noted at 24 hours, 72 hours, and 7 days after spinal anesthesia. The meningeal headache index was used to grade the headache's severity. Result: The incidence of PDPH through 1 week was 4 (16%) for both dexamethasone and the control group, and 2 (8%) for the normal saline group, with non-statistically significant differences (p-value more than 0.05). Additionally, there is no statistically significant difference in headache severity. The onset of headaches was delayed in the normal saline group compared with the control group, p-value less than 0.05. Duration of headache was comparable in the three-study group with a p-value of > 0.05. Conclusion: Both normal saline and dexamethasone are not effective in the prevention of post- dural puncture headache after spinal anesthesia.

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Publication Details

Journal
International Journal of Pharmaceutical and Bio-Medical Science
Published
2025-07-12
DOI
https://doi.org/10.47191/ijpbms/v5-i7-01
Primary Topic
Anesthesia and Pain Management
Type
article
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article

Effect of Intra-Ligamental Injection Before Removal of Spinal Needle After Spinal Anesthesia on Post Spinal Headache, no Injection Versus Normal Saline Versus Dexamethasone

Dr Ali Nima Hassan, Dr Dhiaa Mohammad Jabbar, Dr Farah Salah Mohammed
International Journal of Pharmaceutical and Bio-Medical Science
Anesthesia and Pain Management
article

Effect of Intra-Ligamental Injection Before Removal of Spinal Needle After Spinal Anesthesia on Post Spinal Headache, no Injection Versus Normal Saline Versus Dexamethasone

Dr Ali Nima Hassan, Dr Dhiaa Mohammad Jabbar, Dr Farah Salah Mohammed
article en

Abstract

Among the most frequent side effects of spinal anesthesia is post-dural puncture headache (PDPH), which occurs in 1-40% of scenarios. In forty percent of cases, invasive treatment options such as epidural blood patches may be necessary, and it might result in significant comorbidity. The dural healing is facilitated by fibroblastic growth; this growth is thought to be enhanced by the damage to the surrounding tissues and the presence of a blood clot. Needle trauma, normal saline and dexamethasone all can produce local irritation that might enhance fibroblastic proliferation. Aim of the study: Assessment of intra-ligamental injection of normal saline and dexamethasone on the incidence, duration and severity of post-spinal headache following spinal anesthesia. Patients and Methods: 75 patients were randomly selected and enrolled into this study. They were divided into three equal groups; control group (C) received nothing, group (D) received dexamethasone, and group (N) received normal saline. After performing spinal block with heavy bupivacaine, in groups D and N the needle was withdrawn for about 0.5 cm to make sure the tip of the needle is in the interspinous ligament then either 1 ml of normal saline or 1 ml of dexamethasone solution was injected before complete removal of the needle. The incidence, severity, onset, and duration of PDPH were noted at 24 hours, 72 hours, and 7 days after spinal anesthesia. The meningeal headache index was used to grade the headache's severity. Result: The incidence of PDPH through 1 week was 4 (16%) for both dexamethasone and the control group, and 2 (8%) for the normal saline group, with non-statistically significant differences (p-value more than 0.05). Additionally, there is no statistically significant difference in headache severity. The onset of headaches was delayed in the normal saline group compared with the control group, p-value less than 0.05. Duration of headache was comparable in the three-study group with a p-value of > 0.05. Conclusion: Both normal saline and dexamethasone are not effective in the prevention of post- dural puncture headache after spinal anesthesia.

International Journal of Pharmaceutical and Bio-Medical ScienceVol. 05(07)
University of Alkafeel (IQ), Intensive Care Foundation (AU)
Openalex Percentile: Top 71%
Anesthesia and Pain Management
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