Through its genoprotective, mitochondrial bioenergetic modulation, and antioxidant effects, Fucoxanthin and its metabolite minimize Ochratoxin A-induced nephrotoxicity in HK-2 human kidney cells
Our results suggest that FX and FXL may be effective novel therapies for treating OTA-induced nephrotoxicity in vitro.
Authors
- Neven A. Ebrahim (ORCID: https://orcid.org/0000-0002-7358-6618)
- Shaza A. Alyamani
- Zakariya M. S. Mohammed (ORCID: https://orcid.org/0000-0003-4371-5711)
- Huda A. Al Doghaither (ORCID: https://orcid.org/0000-0002-6192-8326)
- Ayat B. Al‐Ghafari (ORCID: https://orcid.org/0000-0001-9156-4263)
- Ekramy Mahmoud Elmorsy (ORCID: https://orcid.org/0000-0002-7444-2499)
- Gehad E. Elshopakey (ORCID: https://orcid.org/0000-0003-2924-9670)
- Sameh M. Shabana (ORCID: https://orcid.org/0000-0003-0634-7286)
Institutions
- Northern Border University (SA)
- Mansoura University (EG)
- King Abdulaziz University (SA)
- Taibah University (SA)
- University of Business and Technology (SA)
- Delta University for Science and Technology (EG)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1186/s12882-025-04276-z
- Citations
- 2
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Northern Border University