Eficacia de la terapia con láser de baja potencia en la prevención y tratamiento de la mucositis oral en pacientes oncológicos pediátricos: una meta-revisión

This meta-review analyzed four major studies (published between 2021 and 2023) that evaluated photobiomodulation therapy for oral mucositis in pediatric oncology patients. The analysis included 3,314 patients across 154 studies, examining wavelengths (620-970 nm) and power settings (0.005-3.2 W). Results showed significant mucositis severity reduction (RR = 0.35, 95%CI 0.25-0.45), high treatment adherence (91%, 95%CI 88.30-93.70), and notable pain reduction [SMD = -0.85, 95%CI -1.20-(-)0.50]. Using WHO classification systems, positive outcomes were demonstrated across chemotherapy, radiotherapy, and HSCT treatments, supporting PBM's effectiveness in pediatric oncology settings.