Male and female mice are similarly susceptible to chronic nondiscriminatory social defeat stress despite differences in attack frequency from aggressor
These data suggest that CNSDS-defined stress phenotypes are behaviorally relevant across sexes and extend to deficits in complex reward behaviors, supporting CNSDS as a valuable model for studying sex-specific stress outcomes in mood disorders.
Authors
- Katherine Denney (ORCID: https://orcid.org/0000-0003-0803-3037)
- Benjamin A. Samuels (ORCID: https://orcid.org/0000-0003-2535-0376)
- Allyson Bazer (ORCID: https://orcid.org/0000-0001-5858-6823)
- Charles A. Montgomery
- Maria Chacona
- Shriya Vinod
- Urboshi Datta
Institutions
- Rutgers, The State University of New Jersey (US)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1007/s00213-025-06858-z
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute of Mental Health
- National Institute of General Medical Sciences