Efficacy of Platelet-Rich Plasma (PRP) in wound Healing in Superficial Partial Thickness Burn Wounds

Objectives: To determine the efficacy of Platelet-Rich Plasma (PRP) and conventional dressing among patients with Superficial Partial Thickness Burns. Study Design: Randomized controlled trial. Study Duration: March 2025 to May 2025. Place of Study: Allied Burn and Reconstructive Surgery Centre, Allied Hospital, Faisalabad. Materials & Methods: Total 60 patients between the ages of 16 and 65 years with superficial partial thickness burn area of 35% were included. People with full-thickness burns, which damage the entire dermis, chemical, electrical, or friction burns, a history of bleeding disorders, those currently on anticoagulant therapy, or those who are hypersensitive to PRP components, uncontrolled diabetes with a hbA1c level greater than 6, other injuries, or who are already anemic were not allowed to participate. People in group A had PRP done. Thirty patients in Group B were chosen to get treated with standard dressing therapy. We also looked for evidence of epithelialization on the wound surface, such the presence of fresh, pink epithelial tissue, and on the borders of the incision, like the creation of an epithelial "lip. Results: Patients in group A were 37.10 ± 7.81 years old on average, while those in the group B were 37.37 ± 7.63 years old. With a male to female ratio of 2.2:1, 41 (68.33%) of the 60 patients were men and 19 (31.67%) were women. At the end of 9 days of treatment, 18 patients (60.0%) in group A (Platelet-Rich Plasma (PRP)) and 01 patients (3.33%) in group B (conventional dressing) showed efficacy. 0.0001 is the statistically significant p-value. Conclusion: Our research shows that autologous platelet-rich plasma (PRP) is substantially better at healing wounds than standard dressings.