Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature

This case highlights the potential of a tri-modal therapy combining GEMOX-HAIC, lenvatinib, and toripalimab to convert unresectable ICC to a resectable status, thereby potentially improving patient survival by surgical resection. Further clinical trials investigating this regimen are warranted.

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Publication Details

Journal
World Journal of Gastrointestinal Oncology
Published
2025-07-12
DOI
https://doi.org/10.4251/wjgo.v17.i7.108650
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature

Tianzhi Zhang, Yong Fan, Yingzi Huang, You Li et al.
World Journal of Gastrointestinal Oncology
Cholangiocarcinoma and Gallbladder Cancer Studies
article

Pathological complete response in advanced intrahepatic cholangiocarcinoma was achieved through tri-modal therapy: A case report and review of literature

Tianzhi Zhang, Yong Fan, Yingzi Huang, You Li, Di Tang, Gang Deng, Yajun Tang, Min Deng, Ju-Ping Xie
article en

Abstract

This case highlights the potential of a tri-modal therapy combining GEMOX-HAIC, lenvatinib, and toripalimab to convert unresectable ICC to a resectable status, thereby potentially improving patient survival by surgical resection. Further clinical trials investigating this regimen are warranted.

World Journal of Gastrointestinal OncologyVol. 17(7)
Sun Yat-sen University (CN), The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
Good health and well-being
Openalex Percentile: Top 71%
Cholangiocarcinoma and Gallbladder Cancer Studies
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