Pan-cancer analysis of UDP-glucose 6-dehydrogenase in human tumors and its function in hepatocellular carcinoma
Our study revealed that UGDH could be a valuable prognostic biomarker and potential therapeutic target in many cancers, especially liver and lung cancer. UGDH could promote HCC cell proliferation, potentially by modulating the pentose and glucuronate interconversion pathways.
Authors
- Yongan Ye (ORCID: https://orcid.org/0000-0002-3675-9233)
- Li Hou
- Xiaobin Zao (ORCID: https://orcid.org/0000-0002-7533-1301)
- Jiu-Mei Shen
- Ping Zhang (ORCID: https://orcid.org/0000-0001-9163-6191)
- Xu Cao (ORCID: https://orcid.org/0000-0003-1017-4752)
- Xiaoke Li (ORCID: https://orcid.org/0000-0002-1775-3063)
- Shihao Zheng
- Size Li (ORCID: https://orcid.org/0009-0008-3809-0183)
- Jia-Xin Zhang
- Hongbo Du (ORCID: https://orcid.org/0000-0002-5797-1399)
Institutions
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-07-12
- DOI
- https://doi.org/10.4251/wjgo.v17.i7.105981
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94