Optimization of vitamin K antagonist treatment: Near patient monitoring versus standard of care a parallel group clinical trial in older patients with atrial fibrillation
NPTM of VKA treatment in AF-patients does not result in an improved TTR when compared to SOC. All-cause death, total number of minor bleedings and all non-major bleedings may be reduced in NPTM, although the study was not powered for these secondary outcomes. Future studies are needed to determine the cost-effectiveness of NTPM versus SOC.
Authors
- Isabelle Schreiber
- Margriet van Elp (ORCID: https://orcid.org/0009-0004-9293-9441)
- Sjef van de Leur
- Frank G. A. Jansman (ORCID: https://orcid.org/0000-0003-2788-9578)
- Esther van ‘t Riet
- J. R. B. J. Brouwers (ORCID: https://orcid.org/0000-0002-7547-1662)
- Maarten Beinema (ORCID: https://orcid.org/0000-0001-6533-5416)
Institutions
- University of Groningen (NL)
- University Medical Center Utrecht (NL)
- Isala (NL)
- Deventer Ziekenhuis (NL)
Publication Details
- Journal
- European Journal of Clinical Pharmacology
- Published
- 2025-07-12
- DOI
- https://doi.org/10.1007/s00228-025-03878-8
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00