IBS: Pathophysiology and Management Challenges
Irritable Bowel Syndrome (IBS) is a widespread functional gastrointestinal ailment with chronic abdominal pain, change in bowel movements, and reduced quality of life as hallmarks. Unlike organic diseases, IBS is idiopathic—diagnosed in the absence of structural or biochemical disturbances, which makes disease management more difficult. The causes of IBS are heterogeneous: dysregulation of gut-brain axis, visceral hypersensitivity, motility disorders, changes in microbiome, and psychosocial aspects contribute to it. This article explains causes of IBS, symptomatology, diagnostic criteria, and treatment options multidisciplinary with a focus on tailored dietary intervention, medication, psychotherapy, as well as alternative methods.
Authors
- Fahad Said Khan (ORCID: https://orcid.org/0000-0002-4497-9770)
- Gaweł Sołowski (ORCID: https://orcid.org/0000-0002-1793-4008)
- Isaac John Umaru (ORCID: https://orcid.org/0000-0002-2800-0024)
- Mohammed Khudhair Hasan
- Muhammad Akram (ORCID: https://orcid.org/0000-0002-1170-0833)
- Jaouher Ben Ali (ORCID: https://orcid.org/0000-0002-3137-2865)
- Fethi Ahmet Ozdemir
- Abid Mahmood
- Hind A. Abdulghafoor
- Jehan Mohammed Al-Musawi
Institutions
- Tunis University (TN)
- University of Azad Jammu and Kashmir (PK)
- Bingöl University (TR)
- Government College University, Faisalabad (PK)
- University Of Fallujah (IQ)
- Kwararafa University (NG)
- University of Poonch Rawalakot
- Federal University Wukari
- University of Kufa (IQ)
Publication Details
- Journal
- African Journal of Sciences and Traditional Medicine
- Published
- 2025-05-07
- DOI
- https://doi.org/10.58578/ajstm.v2i2.5641
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00