Synthesis of Novel Amino Derivatives of 1,3-Diaza- and 1,3,5-Triazadamantanes
A number of novel diaza- and triazaadamantane derivatives were synthesized by the reactions of 5,7-disubstituted 2-(4-aminophenyl)-1,3-diazaadamantanes, 1,3,5-triazaadamantane-7-amine, and (aminophenyl)(1,3,5-triazaadamantan-7-yl))methanones with anhydrides of substituted succinic and glutaric acids. Some of the synthesized compounds showed a moderate antibacterial activity against both Gram-positive and Gram-negative bacteria.
Authors
- K. A. Gevorkyan (ORCID: https://orcid.org/0000-0003-3604-6038)
- J. A. Avakimyan (ORCID: https://orcid.org/0000-0002-8470-5176)
- A. D. Harutyunyan (ORCID: https://orcid.org/0000-0002-8320-0942)
- R. E. Muradyan (ORCID: https://orcid.org/0000-0002-4110-9454)
- H. M. Stepanyan (ORCID: https://orcid.org/0000-0001-7236-5947)
- M. V. Galstyan (ORCID: https://orcid.org/0000-0002-9475-8810)
- M. V. Aleksanyan
Institutions
- Institute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical Chemistry (AM)
Publication Details
- Journal
- Russian Journal of Organic Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1134/s1234567824601311
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00