Deep Learning Enhanced Neuro Imaging for Early Alzheimer's Risk Assessment

Alzheimer's Disease (AD) is a chronic neurological condition that necessitates early identification for optimal treatment. Conventional identification techniques rely on cognitive assessments and single-modality imaging, which often fail to detect early-stage abnormalities. This study proposes a deep learning-enhanced neuroimaging framework that integrates multimodal brain imaging techniques, including MRI and PET, to improve the timely identification and risk assessment of AD. The proposed approach utilizes CNNs and attention-based advanced architectures to extract subtle biomarkers from neuroimaging data, enabling accurate classification of preclinical and mild cognitive impairment (MCI) stages. A feature fusion strategy enhances the discriminative power of extracted features, leading to improved diagnostic performance. Experimental results on benchmark Alzheimer's datasets demonstrate that the suggested model obtains 95.3% accuracy, 94.7% sensitivity, and 93.9% specificity, outperforming traditional machine learning methods. This research highlights the potential of AI-driven neuroimaging to revolutionize early Alzheimer's detection, offering a non-invasive, automated, and highly reliable assessment tool for clinicians.

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Publication Details

Published
2025-05-01
DOI
https://doi.org/10.1109/iceccc65144.2025.11063850
Primary Topic
Brain Tumor Detection and Classification
Type
article
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article

Deep Learning Enhanced Neuro Imaging for Early Alzheimer's Risk Assessment

Luxhman Gunaseelan, S Karthikeyan, M. Karthi, A Gnanabaskaran
Brain Tumor Detection and Classification
article

Deep Learning Enhanced Neuro Imaging for Early Alzheimer's Risk Assessment

Luxhman Gunaseelan, S Karthikeyan, M. Karthi, A Gnanabaskaran
article en

Abstract

Alzheimer's Disease (AD) is a chronic neurological condition that necessitates early identification for optimal treatment. Conventional identification techniques rely on cognitive assessments and single-modality imaging, which often fail to detect early-stage abnormalities. This study proposes a deep learning-enhanced neuroimaging framework that integrates multimodal brain imaging techniques, including MRI and PET, to improve the timely identification and risk assessment of AD. The proposed approach utilizes CNNs and attention-based advanced architectures to extract subtle biomarkers from neuroimaging data, enabling accurate classification of preclinical and mild cognitive impairment (MCI) stages. A feature fusion strategy enhances the discriminative power of extracted features, leading to improved diagnostic performance. Experimental results on benchmark Alzheimer's datasets demonstrate that the suggested model obtains 95.3% accuracy, 94.7% sensitivity, and 93.9% specificity, outperforming traditional machine learning methods. This research highlights the potential of AI-driven neuroimaging to revolutionize early Alzheimer's detection, offering a non-invasive, automated, and highly reliable assessment tool for clinicians.

Openalex Percentile: Top 78%
Brain Tumor Detection and Classification
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Deep Learning Enhanced Neuro Imaging for Early Alzheimer's Risk Assessment — Luxhman Gunaseelan, S Karthikeyan, et al. · (2025) | TGRS Research Map | TGRS