Genetic Insights in Orthopedics Disorders: Paving the Way for Personalized Treatment
Personalized medicine is becoming a significant focus in many medical specialties, and Orthopedics is no exception. The role of genetic factors in the predisposition, progression, and treatment response of musculoskeletal conditions has been widely studied. This article explores how genetic markers are identified and linked to various Orthopedics conditions, enabling earlier and more precise diagnoses, particularly through genetic testing. It also underlines the potential of pharmacogenomics to personalize pain management and optimize treatments for bone health disorders by considering how genetic variations can affect the effectiveness of medications. Additionally, gene therapy and stem-cell-based regenerative medicine are discussed as promising approaches for tissue regeneration, especially in bone and cartilage repair. With continued advancements in these areas, there is optimism for more personalized and effective treatment strategies that can improve patient outcomes and reduce the need for trial-and-error treatments.
Authors
- Kamran Shirbache (ORCID: https://orcid.org/0000-0002-9042-9534)
Publication Details
- Journal
- Global Journal of Orthopedics Research
- Published
- 2025-04-14
- DOI
- https://doi.org/10.33552/gjor.2025.04.000599
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00