Formulation and Evaluation of Matrix dissolving Tablet of Isoniazid: Controlled Release

Isoniazidis a cornerstone in the treatment of tuberculosis (TB), yet its conventional administrationis associated with challenges such as frequent dosing and potential hepatotoxicity. Matrix dissolving tablet formulations aim to address these issues by providing controlled drug release, enhancing patient compliance, and minimizing side effects. This review explores various formulation strategies, methodologies employed in developing matrix dissolving tablets of isoniazid, emphasizing the role of both natural and synthetic polymers in modulating drug release profiles. The review paper also covers about formulation of matrix dissolving tablet of Isoniazid and its process of granulation, principle of matrix tablet, types of matrix tablet, advantages, and disadvantages e.t.c.